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Animal-Free Recombinant Human ...

Article
Animal-Free Recombinant Human beta-NGF
Product Number
PC-AF-H-B-NGF-250UG
Supplier
Pacific Coast Biologics
Size
250 ug
Description
β-NGF, a neurotrophic factor structurally akin to BDNF, NT-3, and NT-4, is part of the cysteine-knot family of growth factors, characterized by stable dimeric structures. This potent neurotrophic factor operates via its receptor β-NGFR, playing a pivotal role in the development and maintenance of the sensory and sympathetic nervous systems. Additionally, β-NGF functions as a growth and differentiation factor for B lymphocytes, boosting B-cell survival. The active form of Recombinant Human β-NGF is a non-covalently linked homodimer comprising two 13.5 kDa polypeptide monomers, each containing 120 amino acids and three disulfide bonds essential for biological activity.
Category
Proteins, Peptides and Small Molecules
Product Group
Growth Factors, Chemokines & Cytokines
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses
Molecular Weight
27 kDa
Synonyms
beta-nerve growth factor; Beta-NGF; HSAN5; nerve growth factor (beta polypeptide); nerve growth factor, beta subunit; NGFB; pro-nerve growth factor long
Unigene ID
4803
Gene Symbols
NGF
Supplier URL
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