Animal-Free Recombinant Human ...
- Article
- Animal-Free Recombinant Human beta-NGF
- Product Number
- PC-AF-H-B-NGF-2UG
- Supplier
- Pacific Coast Biologics
- Size
- 2 ug
- Description
- β-NGF, a neurotrophic factor structurally akin to BDNF, NT-3, and NT-4, is part of the cysteine-knot family of growth factors, characterized by stable dimeric structures. This potent neurotrophic factor operates via its receptor β-NGFR, playing a pivotal role in the development and maintenance of the sensory and sympathetic nervous systems. Additionally, β-NGF functions as a growth and differentiation factor for B lymphocytes, boosting B-cell survival. The active form of Recombinant Human β-NGF is a non-covalently linked homodimer comprising two 13.5 kDa polypeptide monomers, each containing 120 amino acids and three disulfide bonds essential for biological activity.
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Growth Factors, Chemokines & Cytokines
- Purity
- ≥ 98% by SDS-PAGE gel and HPLC analyses
- Molecular Weight
- 27 kDa
- Synonyms
- beta-nerve growth factor; Beta-NGF; HSAN5; nerve growth factor (beta polypeptide); nerve growth factor, beta subunit; NGFB; pro-nerve growth factor long
- Unigene ID
- 4803
- Gene Symbols
- NGF
- Supplier URL
- Visit supplier product page