Laduviglusib (trihydrochloride...
- Article
- Laduviglusib (trihydrochloride)
- Product Number
- HY-10182B-10MG
- Supplier
- MedChemExpress
- Size
- 10 mg
- Description
- Laduviglusib (CHIR-99021) trihydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib trihydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib trihydrochloride induces autophagy[1][2][3].
- Category
- Lab Reagents & Chemicals
- Product Group
- Biochemicals
- CAS Number
- 1782235-14-6
- Purity
- 99.35
- Molecular Weight
- 574.72
- Shipping Temperature
- RT