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Laduviglusib (trihydrochloride...

Article
Laduviglusib (trihydrochloride)
Product Number
HY-10182B-50MG
Supplier
MedChemExpress
Size
50 mg
Description
Laduviglusib (CHIR-99021) trihydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib trihydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib trihydrochloride induces autophagy[1][2][3].
Category
Lab Reagents & Chemicals
Product Group
Biochemicals
CAS Number
1782235-14-6
Purity
99.35
Molecular Weight
574.72
Shipping Temperature
RT

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