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Recombinant Human PDGF-AB

Article
Recombinant Human PDGF-AB
Product Number
100-00AB-1MG
Supplier
Peprotech
Size
1 mg
Description
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet alpha-granules, and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is a high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Recombinant Human PDGF-AB is a 26.4 kDa disulfide-linked dimer, consisting of one alpha chain and one beta chain (234 total amino acids).
Category
Proteins, Peptides and Small Molecules
Product Group
Growth Factors, Chemokines & Cytokines
Molecular Weight
26.4 kDa
Synonyms
PDGF A-chain; PDGF subunit A; PDGF1; PDGF-A; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha polypeptide; platelet-derived growth factor subunit A; becaplermin; c-sis; epididymis secretory sperm binding protein; IBGC5; PDGF subunit B; PDGF, B chain; PDGF2; PDGF-2; platelet-derived growth factor 2; platelet-derived growth factor B chain; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); platelet-derived growth factor subunit B; platelet-derived growth factor, beta polypeptide (oncogene SIS); proto-oncogene c-Sis; SIS; SSV; Platelet-derived growth factor beta polypeptide; PDGF-1; Platelet-derived growth factor A chain
Unigene ID
5154
Gene Symbols
PDGFA
Articlegroup
Peprotech Bulk
Shipping Temperature
RT

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