Recombinant Human PDGF-AB
- Article
- Recombinant Human PDGF-AB
- Product Number
- 100-00AB-250UG
- Supplier
- Peprotech
- Size
- 250 ug
- Description
- PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet alpha-granules, and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is a high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Recombinant Human PDGF-AB is a 26.4 kDa disulfide-linked dimer, consisting of one alpha chain and one beta chain (234 total amino acids).
- Category
- Proteins, Peptides and Small Molecules
- Product Group
- Growth Factors, Chemokines & Cytokines
- Molecular Weight
- 26.4 kDa
- Synonyms
- PDGF A-chain; PDGF subunit A; PDGF1; PDGF-A; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha polypeptide; platelet-derived growth factor subunit A; becaplermin; c-sis; epididymis secretory sperm binding protein; IBGC5; PDGF subunit B; PDGF, B chain; PDGF2; PDGF-2; platelet-derived growth factor 2; platelet-derived growth factor B chain; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); platelet-derived growth factor subunit B; platelet-derived growth factor, beta polypeptide (oncogene SIS); proto-oncogene c-Sis; SIS; SSV; Platelet-derived growth factor beta polypeptide; PDGF-1; Platelet-derived growth factor A chain
- Unigene ID
- 5154
- Gene Symbols
- PDGFA
- Articlegroup
- Peprotech Bulk
- Shipping Temperature
- RT